After the seizure of Guam from the Spanish as a trophy in its war against Spain, United States government officials were forced to confront the here-to-fore unknown and rather nasty habit of chewing betel nuts for the first time. The nuts are bitter, and stain gums and teeth. By World War II, and after years of active US engagement throughout the South Pacific, the practice would become well known, and even popularized by Rodgers and Hammerstein in their musical South Pacific.
From the song Bloody Mary:
Bloody Mary's chewing betel nuts.
She is always chewing betel nuts.